Kagulire SC, Opendi P, Stamper PD, Nakavuma JL, Mills LA, Makumbi F, Gray RH, Shott JP, Serwadda D, Reynolds SJ.
Int J STD AIDS. 2011 Jun;22(6):308-9. PMID: 21680664. MCID: PMC3726838
Abstract
The performance characteristics of HIV rapid diagnostic tests (RDTs) vary by test and by population. We assessed five commercial RDTs in Uganda where all but one RDT (Determine; Abbott Laboratories, Germany) performed close to manufacturer's expectations. Determine had low specificity (85.2%, positive predictive value 67.3%) due to false-positive results with weak-positive bands. Properly trained staff, good quality control programmes and validation of RDTs with laboratories having confirmatory testing capacity may be warranted to assure accuracy in each setting.